Enrichment analysis of genes dysregulated following Lipopolysaccharide treatment
Canned Analysis
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General Information
AccessionDCA00013575
TitleEnrichment analysis of genes dysregulated following Lipopolysaccharide treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Lipopolysaccharide treated cells and untreated control cells in the lung subsegment cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3088971
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDdrug:2475
Cell Typelung subsegment
Drug NameLipopolysaccharide
Organismhuman
PubChem CID11970143
SMILES IDCCCCCCCCCCCCCCCC1C(OC(C(C1OC(=O)CC(CCCCCCCCCCC)O)O)COC2C(C(C(C(O2)COC3(CC(C(C(O3)C(CO)O)OC4C(C(C(C(O4)C(CO)O)OP(=O)(O)OP(=O)(O)OCCN)OC5C(C(C(C(O5)C(COC6C(C(C(CO6)(C(CO)O)O)O)O)O)OP(=O)(O)O)OC7C(C(C(C(O7)COC8C(C(C(C(O8)CO)O)O)O)O)OC9C(C(C(C(O9)CO)O)O)OC1C(
Characteristic Direction parameters
Control SamplesGSM1004101, GSM1004103, GSM1004105, GSM1004107, GSM1004109, GSM1004111, GSM1004113
Perturbed SamplesGSM1004102, GSM1004104, GSM1004106, GSM1004108, GSM1004110, GSM1004112, GSM1004114
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40885
Gene Expression Omnibus
Alveolar macrophage response to bacterial endotoxin lipopolysaccharide exposure in vivo
7
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