Enrichment analysis of genes dysregulated following Atorvastatin treatment
Canned Analysis
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General Information
AccessionDCA00013583
TitleEnrichment analysis of genes dysregulated following Atorvastatin treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Atorvastatin treated cells and untreated control cells in the Primary umbilical vein endothelial cell cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3087672
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatortimkenny92
CREEDS IDdrug:2484
Cell TypePrimary umbilical vein endothelial cell
Drug NameAtorvastatin
DrugBank IDDB01076
Organismhuman
SMILES IDOC(CC(CC(=O)[O-])O)CCn1c(C(C)C)c(c(c1c1ccc(cc1)F)c1ccccc1)C(=O)Nc1ccccc1
Characteristic Direction parameters
Control SamplesGSM46388, GSM46389
Perturbed SamplesGSM46394, GSM46395
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE2450
Gene Expression Omnibus
Immortalized endothelial cell line response to atorvastatin
7
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