Enrichment analysis of genes dysregulated following 1,25 dihydroxyvitamin d treatment
Canned Analysis
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General Information
AccessionDCA00013591
TitleEnrichment analysis of genes dysregulated following 1,25 dihydroxyvitamin d treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between 1,25 dihydroxyvitamin d treated cells and untreated control cells in the RWPE1 cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3089478
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormmluxy
CREEDS IDdrug:2493
Cell TypeRWPE1 cells
Drug Name1,25 dihydroxyvitamin d
Organismhuman
PubChem CID5280453
SMILES IDCC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C
Characteristic Direction parameters
Control SamplesGSM400051, GSM400052, GSM400053, GSM400054, GSM400059, GSM400060, GSM400061, GSM400062, GSM400067, GSM400068, GSM400069, GSM400070
Perturbed SamplesGSM400055, GSM400056, GSM400057, GSM400058, GSM400063, GSM400064, GSM400065, GSM400066, GSM400071, GSM400072, GSM400073, GSM400074
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15947
Gene Expression Omnibus
1,25 dihydroxyvitamin D effect on prostate epithelial cell line RWPE1: time course
28
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