Enrichment analysis of genes dysregulated following Methylphenidate treatment
Canned Analysis
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General Information
AccessionDCA00013601
TitleEnrichment analysis of genes dysregulated following Methylphenidate treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Methylphenidate treated cells and untreated control cells in the brain cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3087482
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsaulc07
CREEDS IDdrug:2499
Cell Typebrain
Drug NameMethylphenidate
DrugBank IDDB00422
Organismmouse
PubChem CID4158
SMILES IDCOC(=O)C(C1CCCCN1)C2=CC=CC=C2
Characteristic Direction parameters
Control SamplesGSM831337, GSM831338, GSM831339
Perturbed SamplesGSM831340, GSM831341, GSM831342
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE33619
Gene Expression Omnibus
Methylphenidate effect on substantia nigra: dose response
7
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