Enrichment analysis of genes dysregulated following Olanzapine treatment
Canned Analysis
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General Information
AccessionDCA00013615
TitleEnrichment analysis of genes dysregulated following Olanzapine treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Olanzapine treated cells and untreated control cells in the brain frontal cortex tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3087820
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormmluxy
CREEDS IDdrug:2511
Cell Typebrain frontal cortex tissue
Drug NameOlanzapine
Organismrat
PubChem CID4585
SMILES IDCC1=CC2=C(NC3=CC=CC=C3N=C2S1)N4CCN(CC4)C
Characteristic Direction parameters
Control SamplesGSM48559, GSM48577, GSM48578, GSM48579
Perturbed SamplesGSM48580, GSM48581, GSM48582, GSM48583
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2547
Gene Expression Omnibus
Antipsychotic agent olanzapine effect on the brain frontal cortex
7
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