Enrichment analysis of genes dysregulated following Fenretinide treatment
Canned Analysis
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General Information
AccessionDCA00013624
TitleEnrichment analysis of genes dysregulated following Fenretinide treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Fenretinide treated cells and untreated control cells in the CD34+ CML cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3089384
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:2529
Cell TypeCD34+ CML cells
Drug NameFenretinide
DrugBank IDDB05076
Organismhuman
SMILES IDO=C(Nc1ccc(cc1)O)/C=C(/C=C/C=C(/C=C/C1=C(C)CCCC1(C)C)\C)\C
Characteristic Direction parameters
Control SamplesGSM435978, GSM435979, GSM435980
Perturbed SamplesGSM435981, GSM435982, GSM435983, GSM435984, GSM435985
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE17480
Gene Expression Omnibus
Transcriptome profiling of fenretinide-treated and untreated CD34+ cells from 4 CML patients
7
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