Enrichment analysis of genes dysregulated following Temozolomide treatment
Canned Analysis
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General Information
AccessionDCA00013647
TitleEnrichment analysis of genes dysregulated following Temozolomide treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Temozolomide treated cells and untreated control cells in the U87 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3089708
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAliDot
CREEDS IDdrug:2555
Cell TypeU87
Drug NameTemozolomide
DrugBank IDDB00853
Organismhuman
PubChem CID5394
SMILES IDCN1C(=O)N2C=NC(=C2N=N1)C(=O)N
Characteristic Direction parameters
Control SamplesGSM1062690, GSM1062691
Perturbed SamplesGSM1062692, GSM1062693
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE43452
Gene Expression Omnibus
Glioblastoma cells response to Focal Adhesion Kinase Inhibitor Y15 and Temozolomide
21
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