Enrichment analysis of genes dysregulated following Plx4032 treatment
Canned Analysis
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General Information
AccessionDCA00013649
TitleEnrichment analysis of genes dysregulated following Plx4032 treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Plx4032 treated cells and untreated control cells in the COLO829 human melanoma cell line (BRAFV600E mutated) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3089714
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:2557
Cell TypeCOLO829 human melanoma cell line (BRAFV600E mutated)
Drug NamePlx4032
DrugBank IDDB05238
Organismhuman
Characteristic Direction parameters
Control SamplesGSM1225721, GSM1225722
Perturbed SamplesGSM1225723, GSM1225724
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE50649
Gene Expression Omnibus
COLO829 treatment with PLX4032 and/or MITF knockdown
14
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