Enrichment analysis of genes dysregulated following Fgfr-specific pd173074 inhibitor treatment
Canned Analysis
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General Information
AccessionDCA00013671
TitleEnrichment analysis of genes dysregulated following Fgfr-specific pd173074 inhibitor treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Fgfr-specific pd173074 inhibitor treated cells and untreated control cells in the human multiple myeloma cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3088872
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorjustinenoel
CREEDS IDdrug:3244
Cell Typehuman multiple myeloma cell line
Drug NameFgfr-specific pd173074 inhibitor
Organismhuman
PubChem CID1401
SMILES IDCCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C
Characteristic Direction parameters
Control SamplesGSM1267153, GSM1267154, GSM1267155
Perturbed SamplesGSM1267156, GSM1267157, GSM1267158
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE52452
Gene Expression Omnibus
Fibroblast growth factor receptor inhibition effect on malignant urothelial cells deficient in TGF-activated kinase 1
33
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