Enrichment analysis of genes dysregulated following Bexarotene treatment
Canned Analysis
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General Information
AccessionDCA00013776
TitleEnrichment analysis of genes dysregulated following Bexarotene treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Bexarotene treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3089192
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2680
Drug NameBexarotene
DrugBank IDDB00307
Organismhuman
PubChem CID82146
SMILES IDCC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
Characteristic Direction parameters
Control SamplesGSM159355, GSM159356, GSM159357, GSM159358
Perturbed SamplesGSM159359, GSM159360, GSM159361, GSM159362
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE6914
Gene Expression Omnibus
Bexarotene effect on gemcitabine resistant non-small lung cancer cell line
7
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