Enrichment analysis of genes dysregulated following Bexarotene treatment
Canned Analysis
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General Information
AccessionDCA00013777
TitleEnrichment analysis of genes dysregulated following Bexarotene treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Bexarotene treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3087491
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2681
Drug NameBexarotene
DrugBank IDDB00307
Organismhuman
PubChem CID82146
SMILES IDCC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
Characteristic Direction parameters
Control SamplesGSM320837, GSM320841, GSM320845, GSM320849
Perturbed SamplesGSM320838, GSM320842, GSM320846, GSM320850
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE12791
Gene Expression Omnibus
Acquired paclitaxel-resistant MDA-MB-231 cancer cells response to bexarotene treatment
14
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