Enrichment analysis of genes dysregulated following Bortezomib treatment
Canned Analysis
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General Information
AccessionDCA00013780
TitleEnrichment analysis of genes dysregulated following Bortezomib treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Bortezomib treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3088974
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2686
Drug NameBortezomib
DrugBank IDDB00188
Organismhuman
SMILES IDCC(C[C@@H](B(O)O)NC(=O)[C@@H](NC(=O)c1cnccn1)Cc1ccccc1)C
Characteristic Direction parameters
Control SamplesGSM766676, GSM766677, GSM766678
Perturbed SamplesGSM766682, GSM766683, GSM766684
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE30931
Gene Expression Omnibus
Proteasome inhibitor Bortezomib effect on MCF7 breast cancer cells
7
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