Enrichment analysis of genes dysregulated following Imatinib treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00013837
TitleEnrichment analysis of genes dysregulated following Imatinib treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Imatinib treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3087853
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2764
Drug NameImatinib
DrugBank IDDB00619
Organismhuman
PubChem CID5291
SMILES IDCC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
Characteristic Direction parameters
Control SamplesGSM603097, GSM603099, GSM603101
Perturbed SamplesGSM603098, GSM603100, GSM603102
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE24493
Gene Expression Omnibus
Imatinib treatment of chronic myeloid leukemia cell lines: KU-812, KCL-22 and JURL-MK1
12
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.