Enrichment analysis of genes dysregulated following Irinotecan treatment
Canned Analysis
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General Information
AccessionDCA00013838
TitleEnrichment analysis of genes dysregulated following Irinotecan treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Irinotecan treated cells and untreated control cells in the stomach cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3087808
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2767
Cell Typestomach
Drug NameIrinotecan
DrugBank IDDB00762
Organismrat
PubChem CID60838
SMILES IDCCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7
Characteristic Direction parameters
Control SamplesGSM297524, GSM297525
Perturbed SamplesGSM297526, GSM297527
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11722
Gene Expression Omnibus
Gastrointestinal tract response to cytotoxic chemotherapy: time course
21
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