Enrichment analysis of genes dysregulated following Isotretinoin treatment
Canned Analysis
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General Information
AccessionDCA00013843
TitleEnrichment analysis of genes dysregulated following Isotretinoin treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Isotretinoin treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3089727
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2772
Drug NameIsotretinoin
DrugBank IDDB00982
Organismhuman
SMILES IDC/C(=C\C=C\C(=C/C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C
Characteristic Direction parameters
Control SamplesGSM263915, GSM263916, GSM263917
Perturbed SamplesGSM263918, GSM263919, GSM263920
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10432
Gene Expression Omnibus
13-cis retinoic acid effect on SEB-1 sebocyte cell line
12
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