Enrichment analysis of genes dysregulated following Pioglitazone treatment
Canned Analysis
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General Information
AccessionDCA00013860
TitleEnrichment analysis of genes dysregulated following Pioglitazone treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Pioglitazone treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3087953
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2797
Drug NamePioglitazone
DrugBank IDDB01132
Organismmouse
PubChem CID4829
SMILES IDCCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3
Characteristic Direction parameters
Control SamplesGSM806188, GSM806189, GSM806190, GSM806191, GSM806192, GSM806193, GSM806194, GSM806195
Perturbed SamplesGSM806196, GSM806197, GSM806198, GSM806199, GSM806200, GSM806201, GSM806202, GSM806203
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE32536
Gene Expression Omnibus
Long-term pioglitazone effect on triple transgenic model of Alzheimer's disease (3xTg-AD): hippocampus
7
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