Enrichment analysis of genes dysregulated following Propofol treatment
Canned Analysis
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General Information
AccessionDCA00013861
TitleEnrichment analysis of genes dysregulated following Propofol treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Propofol treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3088571
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2804
Drug NamePropofol
DrugBank IDDB00818
Organismhuman
PubChem CID4943
SMILES IDCC(C)C1=C(C(=CC=C1)C(C)C)O
Characteristic Direction parameters
Control SamplesGSM99239, GSM99244, GSM99247, GSM99261, GSM99274, GSM99285, GSM99291, GSM99295, GSM99301, GSM99303
Perturbed SamplesGSM99241, GSM99246, GSM99249, GSM99265, GSM99277, GSM99287, GSM99292, GSM99296, GSM99302, GSM99304
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4386
Gene Expression Omnibus
Sevoflurane and propofol effect on the heart during off-pump coronary artery bypass graft surgery
14
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