Enrichment analysis of genes dysregulated following Tamoxifen treatment
Canned Analysis
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General Information
AccessionDCA00013872
TitleEnrichment analysis of genes dysregulated following Tamoxifen treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Tamoxifen treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3088944
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2820
Drug NameTamoxifen
DrugBank IDDB00675
Organismhuman
PubChem CID2733526
SMILES IDCCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
Characteristic Direction parameters
Control SamplesGSM92147, GSM92148
Perturbed SamplesGSM92152, GSM92153, GSM92154
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE4025
Gene Expression Omnibus
Tamoxifen effect on breast cancer cell line expressing estrogen receptor alpha and beta
7
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