Enrichment analysis of genes dysregulated following Bleomycin treatment
Canned Analysis
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General Information
AccessionDCA00013885
TitleEnrichment analysis of genes dysregulated following Bleomycin treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Bleomycin treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3088777
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2851
Drug NameBleomycin
DrugBank IDDB00290
Organismmouse
PubChem CID5360373
SMILES IDCC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O
Characteristic Direction parameters
Control SamplesGSM50717, GSM50721
Perturbed SamplesGSM50715, GSM50719
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE2640
Gene Expression Omnibus
Bleomycin effect on lungs: dose response and time course
14
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