Enrichment analysis of genes dysregulated following Torcetrapib treatment
Canned Analysis
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General Information
AccessionDCA00013891
TitleEnrichment analysis of genes dysregulated following Torcetrapib treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Torcetrapib treated cells and untreated control cells in the H295R cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3087413
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorshvetank
CREEDS IDdrug:3172
Cell TypeH295R cells
Drug NameTorcetrapib
Organismhuman
PubChem CID159325
SMILES IDCCC1CC(C2=C(N1C(=O)OCC)C=CC(=C2)C(F)(F)F)N(CC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C(=O)OC
Characteristic Direction parameters
Control SamplesGSM399572, GSM399573, GSM399574
Perturbed SamplesGSM399575, GSM399576, GSM399577, GSM399578, GSM399579, GSM399580
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15918
Gene Expression Omnibus
Torcetrapib effect on adrenal carcinoma cell line
14
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