Enrichment analysis of genes dysregulated following Argyrin a treatment
Canned Analysis
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General Information
AccessionDCA00013906
TitleEnrichment analysis of genes dysregulated following Argyrin a treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Argyrin a treated cells and untreated control cells in the MCF7 breast adenocarcinoma cells - 12 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3089074
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3052
Cell TypeMCF7 breast adenocarcinoma cells - 12 Hours
Drug NameArgyrin a
Organismhuman
PubChem CID24978550
SMILES IDCCC1C2=NC(=CS2)C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(=C)C(=O)N(CC(=O)N1)C)C)CC3=CNC4=C3C(=CC=C4)OC)CC5=CNC6=CC=CC=C65
Characteristic Direction parameters
Control SamplesGSM212654, GSM212661, GSM297803
Perturbed SamplesGSM297801, GSM297804
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8565
Gene Expression Omnibus
Argyrin A effect on MCF7 breast cancer cells: time course
14
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