Enrichment analysis of genes dysregulated following Bleomycin treatment
Canned Analysis
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General Information
AccessionDCA00013949
TitleEnrichment analysis of genes dysregulated following Bleomycin treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Bleomycin treated cells and untreated control cells in the LUNG (wild type) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3089333
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3104
Cell TypeLUNG (wild type)
Drug NameBleomycin
DrugBank IDDB00290
Organismmouse
PubChem CID5360373
SMILES IDCC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O
Characteristic Direction parameters
Control SamplesGSM1068446, GSM1068447, GSM1068448
Perturbed SamplesGSM1068449, GSM1068450, GSM1068451
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE43695
Gene Expression Omnibus
Fra-1 deficient lung response to fibrotic agent bleomycin
33
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