Enrichment analysis of genes dysregulated following 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment
Canned Analysis
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General Information
AccessionDCA00013954
TitleEnrichment analysis of genes dysregulated following 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between 2,3,7,8-tetrachlorodibenzo-p-dioxin treated cells and untreated control cells in the Hypothalamus (postnatal day70 male rats exposed in utero to dioxin at gestational day15) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3087805
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3111
Cell TypeHypothalamus (postnatal day70 male rats exposed in utero to dioxin at gestational day15)
Drug Name2,3,7,8-tetrachlorodibenzo-p-dioxin
Organismrat
PubChem CID10852289
SMILES IDCC(C)C=CC(=O)ONC(=O)COC1=CC=C(C=C1)[N+](=O)[O-]
Characteristic Direction parameters
Control SamplesGSM1168492, GSM1168493, GSM1168494
Perturbed SamplesGSM1168495, GSM1168496, GSM1168497
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE48100
Gene Expression Omnibus
Dioxin exposure in utero effect on the hypothalamus at maturity
14
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