Enrichment analysis of genes dysregulated following Neocarzinostatin treatment
Canned Analysis
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General Information
AccessionDCA00013956
TitleEnrichment analysis of genes dysregulated following Neocarzinostatin treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Neocarzinostatin treated cells and untreated control cells in the HEK293 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3089183
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAliDot
CREEDS IDdrug:3113
Cell TypeHEK293
Drug NameNeocarzinostatin
Organismhuman
PubChem CID5282473
SMILES IDCC1C(C(C(C(O1)OC2C3CC#CC4C(O4)(C#CC3=CC2OC(=O)C5=C(C=CC6=C(C=C(C=C65)OC)C)O)C7COC(=O)O7)NC)O)O
Characteristic Direction parameters
Control SamplesGSM28627, GSM28628, GSM28629
Perturbed SamplesGSM28630, GSM28631, GSM28632
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE1676
Gene Expression Omnibus
siRNA knockdown and transcriptional response to DNA damage
35
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