Enrichment analysis of genes dysregulated following Pertuzumab treatment
Canned Analysis
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General Information
AccessionDCA00013968
TitleEnrichment analysis of genes dysregulated following Pertuzumab treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Pertuzumab treated cells and untreated control cells in the SKOV3 ovarian cancer xenograft tumor cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3088085
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3124
Cell TypeSKOV3 ovarian cancer xenograft tumor
Drug NamePertuzumab
DrugBank IDDB06366
Organismhuman
Characteristic Direction parameters
Control SamplesGSM780707, GSM780708, GSM780709, GSM780719, GSM780720, GSM780721
Perturbed SamplesGSM780713, GSM780714, GSM780715, GSM780725, GSM780726, GSM780727
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE31432
Gene Expression Omnibus
Ovarian cancer xenograft tumor response to trastuzumab and pertuzumab
14
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