Enrichment analysis of genes dysregulated following Cetuximab treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00013974
TitleEnrichment analysis of genes dysregulated following Cetuximab treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Cetuximab treated cells and untreated control cells in the CAL27 squamous cell carcinoma (HNSCC) cell line - (15nM for 13 hours) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3089533
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3133
Cell TypeCAL27 squamous cell carcinoma (HNSCC) cell line - (15nM for 13 hours)
Drug NameCetuximab
DrugBank IDDB00002
Organismhuman
Characteristic Direction parameters
Control SamplesGSM1506255, GSM1506256, GSM1506257
Perturbed SamplesGSM1506252, GSM1506253, GSM1506254
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE61495
Gene Expression Omnibus
Overcoming cetuximab resistance in HNSCC: The role of AURKB and DUSP proteins
28
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.