Enrichment analysis of genes dysregulated following 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment
Canned Analysis
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General Information
AccessionDCA00014014
TitleEnrichment analysis of genes dysregulated following 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between 2,3,7,8-tetrachlorodibenzo-p-dioxin treated cells and untreated control cells in the Hematopoietic CD34+ cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3089089
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3189
Cell TypeHematopoietic CD34+ cells
Drug Name2,3,7,8-tetrachlorodibenzo-p-dioxin
Organismhuman
PubChem CID10852289
SMILES IDCC(C)C=CC(=O)ONC(=O)COC1=CC=C(C=C1)[N+](=O)[O-]
Characteristic Direction parameters
Control SamplesGSM595118, GSM595120, GSM595122, GSM595124
Perturbed SamplesGSM595119, GSM595121, GSM595123, GSM595125
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE24193
Gene Expression Omnibus
Hematopoietic CD34+ cells exposed in vitro to dioxin
7
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