Enrichment analysis of genes dysregulated following Mk-886 treatment
Canned Analysis
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General Information
AccessionDCA00014015
TitleEnrichment analysis of genes dysregulated following Mk-886 treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Mk-886 treated cells and untreated control cells in the H720 cell line(lung cancer) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3089267
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJuliana
CREEDS IDdrug:3192
Cell TypeH720 cell line(lung cancer)
Drug NameMk-886
Organismhuman
PubChem CID3651377
SMILES IDCC(C)C1=CC2=C(C=C1)N(C(=C2SC(C)(C)C)CC(C)(C)C(=O)O)CC3=CC=C(C=C3)Cl
Characteristic Direction parameters
Control SamplesGSM71936, GSM71937, GSM71938
Perturbed SamplesGSM71939, GSM71940, GSM71941
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3202
Gene Expression Omnibus
MK886 treatment of H720 non-small cell lung cancer cell line
14
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