Enrichment analysis of genes dysregulated following Lmp-420 treatment
Canned Analysis
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General Information
AccessionDCA00014041
TitleEnrichment analysis of genes dysregulated following Lmp-420 treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Lmp-420 treated cells and untreated control cells in the Primary chronic lymphocytic leukemia cell - 2 uM for 24 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3087379
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3222
Cell TypePrimary chronic lymphocytic leukemia cell - 2 uM for 24 Hours
Drug NameLmp-420
Organismhuman
PubChem CID497668
SMILES IDB(CCCCCN1C=NC2=C1N=C(N=C2Cl)N)(O)O
Characteristic Direction parameters
Control SamplesGSM506907, GSM506909, GSM506911, GSM506913, GSM506915, GSM506917, GSM506919, GSM506921, GSM506923, GSM506925, GSM506927, GSM506929, GSM506931
Perturbed SamplesGSM506908, GSM506910, GSM506912, GSM506914, GSM506916, GSM506918, GSM506920, GSM506922, GSM506924, GSM506926, GSM506928, GSM506930, GSM506932
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE20211
Gene Expression Omnibus
Primary chronic lymphocytic leukemia cell response to purine nucleoside analog LMP-420
7
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