Enrichment analysis of genes dysregulated following Lysophosphatidic acid treatment
Canned Analysis
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General Information
AccessionDCA00014044
TitleEnrichment analysis of genes dysregulated following Lysophosphatidic acid treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Lysophosphatidic acid treated cells and untreated control cells in the AGS gastric adenocarcinoma cells (NET1 knockdown - 65shRNA) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3087367
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3225
Cell TypeAGS gastric adenocarcinoma cells (NET1 knockdown - 65shRNA)
Drug NameLysophosphatidic acid
Organismhuman
PubChem CID3988
SMILES IDCCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)O)O
Characteristic Direction parameters
Control SamplesGSM646073, GSM646074
Perturbed SamplesGSM646067, GSM646068
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE26309
Gene Expression Omnibus
Lysophosphatidic acid effect on RhoA GEF Exchange Factor NET1-deficient, AGS gastric adenocarcinoma cells
49
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