Enrichment analysis of genes dysregulated following Thapsigargin treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00014050
TitleEnrichment analysis of genes dysregulated following Thapsigargin treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Thapsigargin treated cells and untreated control cells in the Immortalized B cells (from MZ twin pairs - African American ancestry) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3087766
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3236
Cell TypeImmortalized B cells (from MZ twin pairs - African American ancestry)
Drug NameThapsigargin
Organismhuman
PubChem CID446378
SMILES IDCCCCCCCC(=O)OC1C2C(=C(C1OC(=O)C(=CC)C)C)C3C(C(CC2(C)OC(=O)C)OC(=O)CCC)(C(C(=O)O3)(C)O)O
Characteristic Direction parameters
Control SamplesGSM494452, GSM494454, GSM494456, GSM494458, GSM494460, GSM494462, GSM494464, GSM494466, GSM494468, GSM494470, GSM494472, GSM494474, GSM494476, GSM494478, GSM494480, GSM494482, GSM494484, GSM494486, GSM494488, GSM494490, GSM494492, GSM494494, GSM494496, GS
Perturbed SamplesGSM494453, GSM494455, GSM494457, GSM494459, GSM494461, GSM494463, GSM494465, GSM494467, GSM494469, GSM494471, GSM494473, GSM494475, GSM494477, GSM494479, GSM494481, GSM494483, GSM494485, GSM494487, GSM494489, GSM494491, GSM494493, GSM494495, GSM494497, GS
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE19519
Gene Expression Omnibus
Endoplasmic reticulum stress effect on lymphoblastoid cells of monozygotic twins
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.