Enrichment analysis of genes dysregulated following Plx4720 treatment
Canned Analysis
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General Information
AccessionDCA00014055
TitleEnrichment analysis of genes dysregulated following Plx4720 treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Plx4720 treated cells and untreated control cells in the HT29 and Colo205 parental colorectal cancer (CRC) cell lines cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3087511
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorPascal
CREEDS IDdrug:3243
Cell TypeHT29 and Colo205 parental colorectal cancer (CRC) cell lines
Drug NamePlx4720
Organismhuman
PubChem CID24180719
SMILES IDCCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Characteristic Direction parameters
Control SamplesGSM846889, GSM846891
Perturbed SamplesGSM846890, GSM846892
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34299
Gene Expression Omnibus
Colon cancer cell lines with acquired resistance to BRAF inhibitor
12
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