Enrichment analysis of genes dysregulated following Nvp-tnks656 (tankyrase inhibitor) treatment
Canned Analysis
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General Information
AccessionDCA00014057
TitleEnrichment analysis of genes dysregulated following Nvp-tnks656 (tankyrase inhibitor) treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Nvp-tnks656 (tankyrase inhibitor) treated cells and untreated control cells in the SW480 cancer cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3088869
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorPascal
CREEDS IDdrug:3247
Cell TypeSW480 cancer cells
Drug NameNvp-tnks656 (tankyrase inhibitor)
Organismhuman
PubChem CID71227201
SMILES IDCOC1=CC=C(C=C1)C(=O)C2CCN(CC2)CC(=O)N(CC3CC3)CC4=NC(=O)C5=C(N4)CCOC5
Characteristic Direction parameters
Control SamplesGSM1340521, GSM1340522
Perturbed SamplesGSM1340525, GSM1340526
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE55624
Gene Expression Omnibus
SW480 KRAS-mutant colorectal cancer cell line response to dual inhibition of tankyrase and MEK: time course
48
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