Enrichment analysis of genes dysregulated following Pyrazinamide treatment
Canned Analysis
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General Information
AccessionDCA00014138
TitleEnrichment analysis of genes dysregulated following Pyrazinamide treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Pyrazinamide treated cells and untreated control cells in the Lung (from B6D2F1 females infected with Mycobacterium tuberculosis) - 63 days post infection cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3088351
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3326
Cell TypeLung (from B6D2F1 females infected with Mycobacterium tuberculosis) - 63 days post infection
Drug NamePyrazinamide
DrugBank IDDB00339
Organismmouse
PubChem CID1046
SMILES IDC1=CN=C(C=N1)C(=O)N
Characteristic Direction parameters
Control SamplesGSM1165966, GSM1165967
Perturbed SamplesGSM1165970, GSM1165971
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE48027
Gene Expression Omnibus
Pyrazinamide effect on pulmonary tuberculosis model : time course
28
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