Enrichment analysis of genes dysregulated following Curcumin treatment
Canned Analysis
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General Information
AccessionDCA00014189
TitleEnrichment analysis of genes dysregulated following Curcumin treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Curcumin treated cells and untreated control cells in the HL-60 leukemia cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3087911
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3425
Cell TypeHL-60 leukemia cells
Drug NameCurcumin
Organismhuman
PubChem CID969516
SMILES IDCOC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
Characteristic Direction parameters
Control SamplesGSM405501, GSM405502
Perturbed SamplesGSM405497, GSM405498
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE16160
Gene Expression Omnibus
Expression data of HL-60 leukemia cells after treatment with Curcumin and TCDD
14
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