Enrichment analysis of genes dysregulated following Ubiquinol treatment
Canned Analysis
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General Information
AccessionDCA00014210
TitleEnrichment analysis of genes dysregulated following Ubiquinol treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Ubiquinol treated cells and untreated control cells in the monocyte cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3089670
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3448
Cell Typemonocyte
Drug NameUbiquinol
Organismhuman
PubChem CID9962735
SMILES IDCC1=C(C(=C(C(=C1O)OC)OC)O)CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C
Characteristic Direction parameters
Control SamplesGSM533554, GSM533555, GSM533556
Perturbed SamplesGSM533557, GSM533558, GSM533559
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE21351
Gene Expression Omnibus
Ubiquinol-induced gene expression signatures are translated into reduced erythropoiesis and LDL cholesterol levels in humans
7
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