Enrichment analysis of genes dysregulated following Leptin treatment
Canned Analysis
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General Information
AccessionDCA00014334
TitleEnrichment analysis of genes dysregulated following Leptin treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Leptin treated cells and untreated control cells in the Gallbladders (from leptin-deficient obese females following daily treatment with 5 ug/g recombinant leptin for 4 weeks) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3087170
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3592
Cell TypeGallbladders (from leptin-deficient obese females following daily treatment with 5 ug/g recombinant leptin for 4 weeks)
Drug NameLeptin
DrugBank IDDB05098
Organismmouse
Characteristic Direction parameters
Control SamplesGSM74081, GSM74083, GSM74171, GSM74189
Perturbed SamplesGSM74190, GSM74191, GSM74192, GSM74194
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE3293
Gene Expression Omnibus
Leptin effect on gallbladder
12
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