Enrichment analysis of genes dysregulated following 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment
Canned Analysis
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General Information
AccessionDCA00014343
TitleEnrichment analysis of genes dysregulated following 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between 2,3,7,8-tetrachlorodibenzo-p-dioxin treated cells and untreated control cells in the 17.5 day fetal hearts - 3ug/kg cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3088771
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3601
Cell Type17.5 day fetal hearts - 3ug/kg
Drug Name2,3,7,8-tetrachlorodibenzo-p-dioxin
Organismmouse
PubChem CID10852289
SMILES IDCC(C)C=CC(=O)ONC(=O)COC1=CC=C(C=C1)[N+](=O)[O-]
Characteristic Direction parameters
Control SamplesGSM60894, GSM60895, GSM60896, GSM60897, GSM60902, GSM60903, GSM60906, GSM60907
Perturbed SamplesGSM60899, GSM60900, GSM60905, GSM60909
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2812
Gene Expression Omnibus
2,3,7,8-tetrachlorodibenzo-p-dioxin effect on cardiovascular development
21
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