Enrichment analysis of genes dysregulated following Simvastatin treatment
Canned Analysis
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General Information
AccessionDCA00014359
TitleEnrichment analysis of genes dysregulated following Simvastatin treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Simvastatin treated cells and untreated control cells in the Lung (from C57BL/6J) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3088002
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3618
Cell TypeLung (from C57BL/6J)
Drug NameSimvastatin
Organismmouse
PubChem CID54454
SMILES IDCCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C
Characteristic Direction parameters
Control SamplesGSM29706, GSM29707, GSM29708
Perturbed SamplesGSM29712, GSM29713, GSM29714
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1871
Gene Expression Omnibus
Inflammatory lung injury and effect of simvastatin
14
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