Small molecules which reverse GHR KO
Canned Analysis
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General Information
AccessionDCA00019676
TitleSmall molecules which reverse GHR KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by GHR KO in the Liver tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f7e0e467bea600fb9e28
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorXavier
CREEDS IDgene:1001
Cell TypeLiver tissue
Gene Symbol (human)GHR
Gene Symbol (mouse)Ghr
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM15491, GSM15492, GSM15493
Perturbed SamplesGSM15497, GSM15498, GSM15499
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE988
Gene Expression Omnibus
Growth hormone receptor mutants
21
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