Small molecules which reverse GHR Mutation (569)
Canned Analysis
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General Information
AccessionDCA00019680
TitleSmall molecules which reverse GHR Mutation (569)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by GHR Mutation (569) in the liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d226cbe467bea600fbb256
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsolomoniyi
CREEDS IDgene:1401
Cell Typeliver
Gene Symbol (human)GHR
Gene Symbol (mouse)Ghr
Organismmouse
Perturbation TypeMutation (569)
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM15491, GSM15492, GSM15493
Perturbed SamplesGSM15488, GSM15489, GSM15490
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE988
Gene Expression Omnibus
Growth hormone receptor mutants
21
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