Small molecules which mimic SOX17 OE
Canned Analysis
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General Information
AccessionDCA00019685
TitleSmall molecules which mimic SOX17 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by SOX17 OE in the CA1 and CA2 embryonic stem cell (ESC) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fe43e467bea600fba0b4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormtahay
CREEDS IDgene:1272
Cell TypeCA1 and CA2 embryonic stem cell (ESC)
Gene Symbol (human)SOX17
Gene Symbol (mouse)Sox17
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM272919, GSM272921
Perturbed SamplesGSM272918, GSM272920
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10809
Gene Expression Omnibus
SOX transcription factor overexpression in embryonic stem cells
35
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