Small molecules which mimic SOX17 OE
Canned Analysis
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General Information
AccessionDCA00019689
TitleSmall molecules which mimic SOX17 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by SOX17 OE in the HESC (CA1 and CA2) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2153de467bea600fbaad0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorantons
CREEDS IDgene:151
Cell TypeHESC (CA1 and CA2)
Gene Symbol (human)SOX17
Gene Symbol (mouse)Sox17
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM272915, GSM272917, GSM272919, GSM272921
Perturbed SamplesGSM272918, GSM272920
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE10809
Gene Expression Omnibus
SOX transcription factor overexpression in embryonic stem cells
35
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