Small molecules which reverse MYC KD
Canned Analysis
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General Information
AccessionDCA00019694
TitleSmall molecules which reverse MYC KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MYC KD in the medulloblastoma cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23878e467bea600fbba24
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorChrisToJ
CREEDS IDgene:712
Cell Typemedulloblastoma
Gene Symbol (human)MYC
Gene Symbol (mouse)Myc
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM550698, GSM550699, GSM550700
Perturbed SamplesGSM550701, GSM550702, GSM550703
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE22139
Gene Expression Omnibus
MYC oncogene overexpression and silencing effect in medulloblastoma DAOY cells
14
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