Small molecules which reverse OLR1 OE
Canned Analysis
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General Information
AccessionDCA00019698
TitleSmall molecules which reverse OLR1 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by OLR1 OE in the HAECT - aortic endothelial cell line - 2 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fae4e467bea600fb9f3c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:459
Cell TypeHAECT - aortic endothelial cell line - 2 Hours
Gene Symbol (human)OLR1
Gene Symbol (mouse)Olr1
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM329070, GSM329082, GSM329092
Perturbed SamplesGSM329062, GSM329079, GSM329090
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE13139
Gene Expression Omnibus
Oxidized low-density lipoprotein effect on LOX-1 overexpressing aortic endothelial cell line HAECT: time course
35
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