Small molecules which mimic FGFR3 KD
Canned Analysis
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General Information
AccessionDCA00019713
TitleSmall molecules which mimic FGFR3 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by FGFR3 KD in the RT112 - Bladder cancer cell line - (shRNA 2-4) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fed4e467bea600fba0f6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1018
Cell TypeRT112 - Bladder cancer cell line - (shRNA 2-4)
Gene Symbol (human)FGFR3
Gene Symbol (mouse)Fgfr3
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1007043, GSM1007044, GSM1007045
Perturbed SamplesGSM1007034, GSM1007047, GSM1007048
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE41035
Gene Expression Omnibus
Fibroblast growth factor receptor 3 depletion effect on bladder cancer cell line RT112
85
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