Small molecules which reverse NRAS DEPLETION - siRNA siMut12
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00019740
TitleSmall molecules which reverse NRAS DEPLETION - siRNA siMut12
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NRAS DEPLETION - siRNA siMut12 in the 224 melanoma cell line - 1 Day cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2049ce467bea600fba382
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1024
Cell Type224 melanoma cell line - 1 Day
Gene Symbol (human)NRAS
Gene Symbol (mouse)Nras
Organismhuman
Perturbation TypeDEPLETION - siRNA siMut12
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM312684, GSM312685, GSM312686
Perturbed SamplesGSM312690, GSM312691, GSM312692
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE12445
Gene Expression Omnibus
Oncogenic NRAS depletion effect on melanoma cell lines: time course
77
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.