Small molecules which reverse CFTR OE
Canned Analysis
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General Information
AccessionDCA00019768
TitleSmall molecules which reverse CFTR OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CFTR OE in the Lungs - Heterozygous transgenic cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20915e467bea600fba57a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1035
Cell TypeLungs - Heterozygous transgenic
Gene Symbol (human)CFTR
Gene Symbol (mouse)Cftr
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM101260, GSM101261, GSM101264
Perturbed SamplesGSM101258, GSM101262, GSM101266
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4512
Gene Expression Omnibus
Cystic fibrosis transmembrane conductance regulator CFTR transgene overexpression effect on lungs
14
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