Small molecules which mimic PTGS2 INHIBITION
Canned Analysis
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General Information
AccessionDCA00019771
TitleSmall molecules which mimic PTGS2 INHIBITION
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PTGS2 INHIBITION in the Colorectal adenocarcinoma cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20924e467bea600fba580
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1037
Cell TypeColorectal adenocarcinoma
Gene Symbol (human)PTGS2
Gene Symbol (mouse)Ptgs2
Organismhuman
Perturbation TypeINHIBITION
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM283128, GSM283130, GSM283131, GSM283133, GSM283137, GSM283139, GSM283140, GSM283141, GSM283143, GSM283144, GSM283146, GSM283149
Perturbed SamplesGSM283127, GSM283129, GSM283132, GSM283134, GSM283135, GSM283136, GSM283138, GSM283142, GSM283145, GSM283147, GSM283148
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11237
Gene Expression Omnibus
Cyclooxygenase-2 inhibitor celecoxib effect on colorectal adenocarcinoma
19
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