Small molecules which reverse UPF1 KD
Canned Analysis
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General Information
AccessionDCA00019774
TitleSmall molecules which reverse UPF1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by UPF1 KD in the Hela cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20902e467bea600fba572
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1039
Cell TypeHela cells
Gene Symbol (human)UPF1
Gene Symbol (mouse)Upf1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM29530, GSM29531
Perturbed SamplesGSM29532, GSM29534
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1703
Gene Expression Omnibus
RENT1 nonsense-mediated mRNA decay component knockdown
7
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